Abstract
To elucidate risk factors for hypertension, the relationships among the incidences of hypertension, diabetes mellitus, obesity and hypertriglyceridemia were examined in the4, 114 Japanese subjects (1, 978men and2, 136 women).Significant positive correlations among blood pressure, body mass index, plasma glucose and triglyceride levels were identified.Subjects with diabetes mellitus had a 1.59-fold (95%CI1.08-2.34) higher incidence of hypertension compared with that of normal subjects.Also, obese subjects had a1.85-fold (1.47-2.34) higher incidence of hypertension compared with that of normal subjects. Subjects with hypertriglyceridemia had a1.41-fold (1.15-1.72) higher incidence of hypertension compared with that of normal subjects.The combination of diabetes mellitus, obesity and hypertriglyceridemia had a5.14-fold (2.67-9.92) higher incidence of hypertension compared with normal subjects.
These findings demonstrate that abnormalities in glucose tolerance, obesity and hypertriglyceridemia are independent factors of hypertension.