Journal of Toxicologic Pathology
Online ISSN : 1881-915X
Print ISSN : 0914-9198
ISSN-L : 0914-9198
Case Reports
Early-Stage Goniodysgenetic Glaucoma in a Young Beagle Dog
Osamu SawamotoKen-ichi Umeoka
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2004 Volume 17 Issue 4 Pages 275-278

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Abstract
Signs of glaucoma such as greenish eyes were observed clinically in a 9-month-old male beagle dog. Histopathologically, the glaucomatous eye was characterized by goniodysgenesis (the absence of a trabecular meshwork) in the filtration angle. Spheroid bodies suggestive of axonal degeneration were observed in the axons posterior to the lamina cribrosa, although cupping of the optic nerve head was not seen. The diagnosis of early-stage glaucoma due to goniodysgenesis was made based on the animal's clinical course and histopathological findings. In addition, narrowing of the episcleral veins, fluid retention in the ciliary processes, and retinal edema were noted. The above findings support the concept that glaucomatous optic neuropathy may be caused by a reduction in blood flow rather than an increase in intraocular pressure.
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© 2004 The Japanese Society of Toxicologic Pathology
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