Abstract
Cypermethrin is a synthetic pyrethroid insecticide used to control pests in domestic, industrial and agricultural fields. Pesticides carried away by rains and floods in to the aquatic body. The lipophilicity nature of these pesticides makes easy entrance into the body of aquatic animals even in low concentration. The endocrine disruptive activity of cypermethrin on Oreochromis mossambicus was tested. The fish were exposed to 0, 0.0001, 0.0002 and 0.0003ppm cypermethrin pesticide concentration. The respiratory stress, erratic swimming and instant death of fish were observed. The mortality is concentration and duration dependent. The lethal concentration at 50% (LC50) 0.001ppm for 96h of exposure has been detected. Histopathological changes such as condensation of the nuclei, infiltration of red blood cells in the interstitial space, degeneration in seminiferous tubules and severe hemolysis were observed in testis. Likewise, oocyte atresia and vacuolation were identified in ovary of fish. The intersex development in ovary is establishing the endocrine disruptive action. Thus, cypermethrin function as endocrine disruptive chemical in fish.
