Historical control data for Embryo-fetal studies in Sprague-Dawley rats

Abstract

The purpose of this study is to collect and summarize historical control data for Embryo-fetal development studies using Sprague-Dawley rats (Crl:CD(SD)), laboratory animals having a uniform quality from Charles River Inc. The background data were obtained from pregnant Sprague-Dawley rats in the control groups of our previous toxicity studies. The data includes reproductive and developmental parameters associated with fetus after caesarean section and fetal external, skeletal and visceral alterations, etc. These background control data will contribute to evaluation of reproductive and developmental toxicity studies especially embryo-fetal studies for rodents.