Abstract
As the urethra is the main place of entry for sexually transmitted pathogens, histopathologic evaluation of the urethral prostate complex is an important component of drug safety assessment and evaluation environmental toxicants. The present study investigated in rats the morphologies of prostatic complex including ampullary glands following prenatal di(n-butyl) phthalate. In rodent, although the prostate complex is designated as prostate: ventral, lateral, dorsal lobes; and coagulating gland, ampullary glands, and seminal vesicle, Aumuller et al., (2012) recently described the prostatic urogenital duct system of male rat, while there are still some controverisial. The ejaculatory sinus had been described to compose binding the ampullary duct and the seminal vesicle duct, and many ducts of prostatic lobes opened at this sinus. Our previous study revealed that the seminal vesicle duct drained into the ampullary duct at quite nearly position at the seminal colliculus with the slit like opening into urethra, and no prostatic lobes duct drain at these structures. In this study we evaluated the influence of prenatal di(n-butyl) phthalate for the ejaculatory system at the prostatic complex.
