臨床副作用の予測における非臨床からのアプローチ：endogenous metabolite解析によるアセトアミノフェン誘発性肝機能障害の評価法

近藤 千真; 豊田 薫; 山田 直人; 鈴木 優典; 高橋 統一; 小林 章男; 公納 秀幸; 正田 俊之; 菅井 象一郎

doi:10.14869/toxpt.42.1.0_S2-4

The 42nd Annual Meeting of the Japanese Society of Toxicology

Session ID : S2-4

DOI https://doi.org/10.14869/toxpt.42.1.0_S2-4

Conference information

Host: The Japanese Society of Toxicology

Symposium 2

A nonclinical approach to side-effects prediction in susceptible patients: Evaluation methods of acetaminophen-induced chronic hepatotoxicity by endogenous metabolite analyses

*Kazuma KONDO, Kaoru TOYODA, Naohito YAMADA, Yusuke SUZUKI, Tadakazu TAKAHASHI, Akio KOBAYASHI, Hideyuki KUNO, Toshiyuki SHODA, Shoichiro SUGAI

Author information

*Kazuma KONDO
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Kaoru TOYODA
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Naohito YAMADA
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Yusuke SUZUKI
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Tadakazu TAKAHASHI
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Akio KOBAYASHI
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Hideyuki KUNO
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Toshiyuki SHODA
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.
Shoichiro SUGAI
Toxicology Research Laboratories, Central Pharmaceutical Research Institute, JAPAN TOBACCO INC.

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