Host: The Japanese Society of Toxicology
Name : The 47th Annual Meeting of the Japanese Society of Toxicology
Date : 2020 -
Accurate hazard identification is the first step of risk assessment which is an effective tool of risk management. In line with UN Sustainable Development Goals, risk management of hazardous chemical is one of the key elements. Objective is to develop a novel approach on hazard identification.
Chemicals used in Oil and Gas company were evaluated their reproductive toxicity by regulatory agency classification (The Globally Harmonized System of Classification and Labelling of Chemicals, GHS). Secondly, known or presumed reproductive toxicants (GHS Category 1) were further analyzed with carcinogenicity and germ cell mutagenicity for prioritization purpose.
We found substantial disagreement in hazard classification between agencies. An inconsistent hazard classification for the same chemical may result in inconsistent risk assessment outcomes. As misjudgement of hazard identification e.g. under estimation, may result in the potential health risks, the most stringent classification was adopted. It is also found that only limited agencies provided data/ evidence based justification of classifications.
We develop a novel and sustainable approach for hazard identification of chemicals used in Oil and Gas company by using publicly available regulatory databases. It is a cost minimum approach and applicable not only for health hazard, but also for physical chemical hazard and environmental hazard. The approach is not limited to Oil and Gas company use but broader, e.g. small and medium industries which may have limited toxicological expertise and funding.
