Accessing Marketed Drug Information to Inform PreClinical Safety

Abstract

Marketed and withdrawn drugs provide a rich source of information on the clinical effects of pharmacological intervention which can be brought back in to the Pre-Clinical space to improve the translational and predictive power of non-clinical assays and models. Accessing adverse event report data (FAERS) and clinical PK in a structured manner, through PharmaPendium, enables improved understanding of the performance non-clinical assays and facilitates more detailed risk assessment for candidate drugs.