Annual Meeting of the Japanese Society of Toxicology
The 47th Annual Meeting of the Japanese Society of Toxicology
Session ID : S12-1
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Symposium 12
in silico method for risk assessment of chemicals in food with trace levels
*Atsushi ONO
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CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract

Various chemicals present in food such as additives, pesticides, food contact materials, etc.. Toxicological information is very limited for more than thousands of compounds of these other than additives and pesticide. Recently, in silico methods are used for risk assessment of compounds that have limited toxicity information at trace levels in foods. The Threshold of Toxicological Concern (TTC) approach is a method to set a pragmatic threshold below which concerns for adverse effects become negligible, used for risk assessment of food flavors. in silico evaluation for genotoxicity has been adopted for assessment of pesticide metabolites by JMPR and EFSA.

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