Understanding of unrecognized effects of low molecular weight compounds by a decomposition analysis

Abstract

Low molecular weight compounds such can interact with multiple targets, which often causes harmful unrecognized effects, even by the developers. To understand the multiple effects of a compound, omics analysis is a suitable choice because it converts the biological information of a specimen into the numeric one without bias, based on its comprehensiveness.

We have developed a novel analysis method, orthogonal linear separation analysis (OLSA), whose advantage is easiness for biologists to understand the outcome of the unbiased data analysis. We introduce the framework and the application.