Host: The Japanese Society of Toxicology
Name : The 47th Annual Meeting of the Japanese Society of Toxicology
Date : 2020 -
The EU Cosmetics Directive ban on animal in vivo testing and its marketing ban have led the cosmetics industry to develop alternatives to animal testing, and Shiseido has established a weight-of-evidence based safety assurance system that doesn’t test on animals. As for photo-sensitization, the current non-animal method is not enough to test cosmetic materials, and thus we have been developing several in vitro tests (e.g. photo-DPRA, photo-KeratinoSensTM and photo-h-CLAT) corresponding to the Adverse Outcome Pathway. In this lecture, we will introduce our efforts to develop a photo-sensitization assessment system and the challenges for the safety assurance of cosmetics.
