Host: The Japanese Society of Toxicology
Nanomaterials have unique physicochemical properties and are used in various fields. However, the adverse effects of nanomaterials on human health have not been fully evaluated. In this study, we applied the human Cell Line Activation Test (h-CLAT), and evaluated the antigen-presenting cell activation ability of silver nanoparticles and silver nitrate. It was suggested that the activation of antigen-presenting cells by silver nanoparticles was due to the silver ions released from the silver nanoparticles, in other words, the released silver ions have antigenicity.
