Host: The Japanese Society of Toxicology
In this alternative method, all 15 lipstick/lip cream raw materials were judged to be non-irritating. Eye irritation data for 32 chemical substances, all 22 raw materials distinguished to GHS categories 1, 2A and 2B were judged to be irritating. 6 raw materials including to the 10 raw materials distinguished to NC, were judged to be non-irritating, but other 4 raw materials were judged to be irritating. These results indicated a possibility of the evaluation for irritating of raw materials by using the criteria of our alternative method. In addition, we will demonstrate some results of biochemical analysis in this report.