QC automation for SEND numerical data using KNIME

Abstract

We would like to introduce the automatic quality check (QC) workflow for numerical SEND data, obligated to submit to FDA, implemented by open source platform KNIME and the improvement for time-consuming QC tasks. We can finish QC for all numerical data in several tens of seconds using KNIME workflow and obtain QC results as Excel files with highlighting improper matching points. Since comparison data source is the text file converted as general-purpose un-pivot format from the Appendix, our QC workflow is applicable to any data from various types of toxicity test systems.