Host: The Japanese Society of Toxicology
Cellulose nanofibrils (CNFs), also known as cellulose nanofibers, there is a concern about risks of carcinogenicity or mesothelioma. A battery of three commonly used assays, namely Ames test, an in vitro chromosomal aberration test, and a mammalian erythrocyte micronucleus test illustrated that the phosphorylated CNFs examined in this study did not induce genotoxicity. We believe that these results will be useful for predicting the human carcinogenic risk of CNFs and accelerate their industrial application. This study was supported by project grants from the New Energy and Industrial Technology Development Organization (NEDO).