Host: The Japanese Society of Toxicology
Anti-infective agents are commonly used during pregnancy because treatment of infections is critical to the health of a mother and her fetus. There have been no large-scale studies addressing safety of many classes of anti-infectives and vaccines during pregnancy. Among the antibiotics, penicillins, cephalosporins and macrolides have been used for a long time without much concern about their effects on the fetus. Vaccines are used during pregnancy to prevent maternal infection and to provide protection for the newborn through passive immunization.
