Neurobehavioral toxicity induced by exposure of low-level chemical substances in early life and its evaluation -Focusing on the analysis of the neurobehavioral effects of neonicotinoid exposure on mice-

Abstract

Although the risk assessments are necessary to prevent the health hazard induced by chemical exposure, several harmful effects on brain functions have been still represented. Recently, chemical exposure to mammals in the prenatal, early postnatal or juvenile period has been recognized as a potential inducer of the effects on the nervous systems in adulthood.

In this symposium, we will report the results of the emotional/cognitive behavior tests and neuroscientific analyses of adult male mice induced by low-level, chronic chemical exposure in early life, focusing on examples of neonicotinoids.