Host: The Japanese Society of Toxicology
Pulmonary delivery of drugs has become an attractive target and of great interest in the medication as the lung is capable of absorbing pharmaceuticals either for local deposition or for systemic delivery. Targeted drug delivery to lung alveolar region is demanded for the treatment of COVID-19. In this presentation, we will outline the recent advances in mass spectrometry imaging for visualizing the distribution of administered drugs and their metabolites in tissue sections. Then, we will introduce a newly developed inhalation exposure system and share our knowledge obtained in our recent investigations. We hope that our presentation would contribute the efficient development of useful drugs.
