Host: The Japanese Society of Toxicology
Name : The 49th Annual Meeting of the Japanese Society of Toxicology
Date : June 30, 2022 - July 02, 2022
The INHAND Proposal (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) has been operational since 2005. A Global Editorial Steering Committee (GESC) helps coordinate overall objectives of the project. Development of harmonized terminology for each rodent organ system or non-rodent species is the responsibility of the Organ Working Groups or Non-rodent Working Groups respectively, drawing upon experts from North America, Europe and Japan.
Great progress has been made with 15 rodent organ systems published in Toxicologic Pathology and in Journal of Toxicologic Pathology as supplements and on a web site: www.goReni.org. A comprehensive review of all rodent systems to standardize terminology common to organ systems was completed and terminology updated in goRENI. Recommendations of the Apoptosis/Necrosis Working Group have been published. The mini-pig and dog have been published in Toxicologic Pathology and non-human primate and rabbit have been published in the Journal of Toxicologic Pathology in 2021. The manuscript on fish will be available for review in 2022. A new group has been formed to address terminology in non-rodent ocular toxicity studies. INHAND guides offer terminology, diagnostic criteria, differential diagnoses and guidelines for recording lesions in toxicity and carcinogenicity studies. The guides provide representative photo-micrographs of morphologic changes, information regarding pathogenesis, and key references.