Abstract
International Life Sciences Institute Japan (ILSI Japan) launched the Alternative Animal Testing Promotion (AAT) project in food sector (AAT project) in 2018. The project aims to establish more predictive evaluation approaches for humans that do not rely on animals, and to advance the sophistication and efficiency of food safety and functionality evaluation. In this project, food-related companies are participating and collaborating with academia to promote research to accelerate alternative approaches, to collect information on the latest technologies, and to disseminate information to build consensus. As research themes, we are working on the construction of a toxicity database of food ingredients for toxicity prediction by effectively utilizing existing toxicity test information, the construction of a technology for predicting food exposure in the body, and the development of animal-independent safety assessment strategies and case reports at the same time. In this session, we will present the current activities and challenges of the ILSI Japan AAT project on NAM-based assessment strategies in the food industry.
