Journal of Trainology
Online ISSN : 2186-5264
ISSN-L : 2186-5264
Short Communication
Changes in cell free DNA during a college soccer season
Jeremy A. GentlesWilliam G. HornsbyHoward S. GrayJonathan A. MillerAndrew R. DotterweichCharles A. StuartMichael H. Stone
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2015 Volume 4 Issue 1 Pages 25-31


Objectives: This study investigated chronic changes in cell free DNA (cf-DNA) throughout a collegiate soccer season. The relationship between cf-DNA, C-reactive protein (CRP), creatine kinase (CK), testosterone (T), cortisol (C), testoster one-cortisol ratio (T:C), body mass and body composition were also examined. Design: Longitudinal study design with repeated measures and group comparisons. Methods: Twenty three NCAA Division I male soccer players were divided into two groups. Starters were placed in Group 1 (G1) and non-starters were placed in Group 2 (G2). cf-DNA, CRP, CK, T, C, T:C, body mass and body composition were taken three times, corresponding to pre-season, approximately mid-season and immediately after the concluding the season. Results: In G1, cf-DNA, CRP, CK, cf-DNA %∆, CRP %∆ and, CK %∆ were all statistically higher at T2 and T3 than T1. In G2, CRP %∆ was statistically higher at T2 than T1. In G2, cf-DNA %∆, CRP %∆ and CK %∆ were higher at T2 and T3 than T1. Conclusions: This suggests that cf-DNA may be a useful marker that can reflect accumulated soccer training and competi tive stressors.

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© 2015 Active Aging Research Center
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