Translational and Regulatory Sciences
Online ISSN : 2434-4974
RS
Use of non-animal test methods in the safety assessment of chemicals
Hajime KOJIMA
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JOURNALS FREE ACCESS

2019 Volume 1 Issue 2 Pages 66-72

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Abstract

EU and US proposals for a paradigm shift in toxicity testing have brought about a worldwide evolution in the safety assessment of chemicals by means of novel approach methods (NAM) that do not use animals. In Japan, as well, despite the fact that there have been no changes in regulation of cosmetics, pharmaceuticals, and other chemical substances, a number of manufacturers have voluntarily discontinued the use of animal testing, and we must now give serious consideration to means for ensuring the safety of chemicals without the use of animal testing in accordance with the international harmonisation. The expanding use of non-animal test methods in the safety assessment of chemicals continues to merit close scrutiny.

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© 2019 Catalyst Unit

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