Possible renoprotective effect of lactotripeptides: A brief review

Abstract

Chronic kidney disease (CKD), an important worldwide public health problem, is closely associated with the risk factors for cardiovascular disease (CVD). Ensuring a healthy environment by making lifestyle modifications is important for the prevention of CKD and CVD. In addition, the use of dietary supplements may be a complementary approach to preventing CKD and CVD. Several meta-analyses have demonstrated the blood pressure-lowering effect of lactotripeptides that are thought to occur via angiotensin converting enzyme inhibitory activity, at least in part, which also offers renal protection. Therefore, based on current findings, this brief review discusses the possibility of lactotripeptide supplements for renal protection.