Abstract
In order to obtain useful metabolites from bivalves composing chemosynthetic communities, their constituents were screened for inhibitory activities toward biologically important glycosidase, α-glucosidase, β-glucosidase, and β-glucuronidase, reactions. The bivalves examined included a vesicomyid clam Calyptogena soyoae and a deep-sea mussel Bathymodiolus platifrons collected around cold seeps in Sagami Bay, central Japan. Inhibition assays for glycosidase reactions were performed using an agar plate method. The constituents of C. soyoae showed potent inhibition toward all glycosidase reactions examined, however those of B. platifrons showed no inhibition. These results suggest that C. soyoae would have more potent metabolic activity of organic compounds than B. platifrons and would contain useful chemical compounds.
