Abstract
Trimetazidine is an anti-ischemic agent. The structure of trimetazidine hydrochloride, C14H22N2O3·HCl, was determined by X-ray crystallography. The compound crystallizes in a monoclinic system, space group P21/c and cell parameters: a = 21.548(1)Å, b = 7.6273(3)Å, c = 9.5982(5)Å, β = 100.651(2)°, Z = 4, V = 1550.32(12)Å3. The crystal structure was solved by direct methods and refined by full-matrix least-squares on F2 to final values of R1 = 0.055 and wR2 = 0.118.
