Cesium Distribution in Renal Tissues by High-Energy Synchrotron Radiation X-ray Fluorescence Analysis

Abstract

To investigate cesium (Cs) distribution in tissues, high-energy synchrotron radiation X-ray fluorescence (SR-XRF) analysis with microprobe was applied to Cs imaging of mice renal specimens. Cs images were constructed using the intensity data of Cs Kα line (30.968 keV) at each point obtained by scanning the specimens with microbeam (1.0 μm×1.0 μm, 37 keV). The detection limit evaluated with thin section standards of Cs was 6 μg/g (counting time, 10 sec). Clear images of Cs corresponding to fine tissue structures were obtained from renal specimens of mice exposed to Cs (50 mg/kg, oral). Cs was found in the medulla and the outer strip of the outer medulla.