Abstract
The case is a male in his early seventies. We performed endoscopic submucosal dissection（ESD）for superficial esophageal cancer in the mid-esophagus. During procedure, the patient exhibited tachycardia and hypertension, and when treated with nicardipine for the same, he suddenly went into temporary cardiac arrest. His heart was quickly restarted by performing cardiac massage. Subsequently, under the observation of a cardiovascular internist ready for transcutaneous pacing, the procedure was continued and the lesion completely resected. On using a Holter electrocardiogram postoperatively, the patient was diagnosed with sick sinus syndrome. We hypothesize that the submucosal epinephrine injection administered during esophageal ESD was related to the tachycardia and hypertension, and we consider this is a rare case of esophageal ESD during which cardiac arrest due to sick sinus syndrome occurred after nicardipine administration.
