Abstract
A 70s-year-old man visited a nearby hospital with the complaint of a difficulty in swallowing lasted for approximately one month. Upper gastrointestinal endoscopic examination revealed tumorous lesion in the esophagus and stomach. We diagnosed endocrine cell carcinoma of the esophagus and gastric poorly differentiated adenocarcinoma with multiple metastasis in lymph nodes and the liver. Chemotherapy using CPT-11 and CDDP were successfully performed, then the regimen was changed to CPT-11 and CBDCA because of renal dysfunction. Now, from the diagnosis 9 months later, the chemotherapy still continues without exacerbation of the cancer. Endocrine cell carcinoma of the esophagus with gastric adenocarcinoma is a very rare disease and has no treatment guideline. In this case, we selected chemotherapy same as lung small cell carcinoma that performed successfully.
