Japanese Journal of Infectious Diseases
Online ISSN : 1884-2836
Print ISSN : 1344-6304
ISSN-L : 1344-6304
Short Communication
In Vitro Antibiotic Susceptibility of Francisella tularensis Isolates from Japan
Akitoyo HottaOsamu FujitaAkihiko UdaNeekun SharmaKiyoshi TanabayashiYoshie YamamotoAkio YamadaShigeru Morikawa
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2013 Volume 66 Issue 6 Pages 534-536


The antibiotic susceptibilities of 36 isolates of Japanese Francisella tularensis, an etiological agent of the zoonotic disease tularemia, were analyzed using the E test. All the isolates were susceptible to ciprofloxacin, doxycycline, erythromycin, and gentamicin but resistant to benzylpenicillin and cephalothin. The susceptibility to seven other β-lactams (aztreonam, cefotaxime, cefoxitin, ceftriaxone, cefuroxime, imipenem, and meropenem) varied among the isolates. These findings suggest that the guidelines for the antibiotic treatment of tularemia issued by the World Health Organization are appropriate for Japanese tularemia patients.

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