Abstract
Clostridium difficile PCR ribotype 027 is hypervirulent that caused significant nosocomial diarrhea in many countries, but not yet reported and isolated in Taiwan previously. Here, we presented the characteristics of a case of C. difficile PCR ribotype 027 identified in Taiwan. Taiwan is located in a key traffic center of Asia. This report is important for hospital and public health administration in Asia to be alert and closely monitor the emergence of this hypervirulent strain to avoid potential outbreaks occurred.