Abstract
Dengue fever is an acute, mosquito-borne, febrile illness caused by Flavivirus spp., which is a problem in Africa, South and Southeast Asia, Latin America, and the Caribbean. A dengue outbreak occurred after nearly 70 years of absence or no detection, and 158 autochthous cases occurred in Japan from August to October 15, 2014. The most competent mosquito vectors for dengue virus transmission were Aedes aegypti and A. albopictus. Since A. albopictus is widely distributed throughout Japan and A. aegypti recently invaded Japan by airplane, we examined the susceptibility of these species to infection by dengue virus (DENV).