Clonal Spread of Enterotoxigenic Escherichia coli O128:H45 strain in the neonate units

Mei Zeng; Wenjing Shi; Hailing Chang; Aimin Wang; Leiyan He; Pan Fu; Xuebin Xu; Chuanqing Wang

doi:10.7883/yoken.JJID.2015.092

This article has now been updated. Please use the final version.

Clonal Spread of Enterotoxigenic Escherichia coli O128:H45 strain in the neonate units

Mei Zeng, Wenjing Shi, Hailing Chang, Aimin Wang, Leiyan He, Pan Fu, Xuebin Xu, Chuanqing Wang

Author information

Keywords: enterotoxigenic Escherichia coli, neonates, nosocomial infection

JOURNAL FREE ACCESS Advance online publication

Article ID: JJID.2015.092

DOI https://doi.org/10.7883/yoken.JJID.2015.092

The final version of this article is now available: Vol. 69 (2016), No. 2 pp. 127-130

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Abstract

Enterotoxigenic Escherichia coli (ETEC) has the potential to cause nosocomial infantile diarrhea in the hospital settings. We detected 12 ETEC serotype O128:H45 isolates from diarrheal neonates in the neonate unit during the period of July-October in 2012. These babies developed hospital-acquired diarrhea or were epidemiologically related. Pulsed-field gel electrophoresis analysis and multilocus sequence typing of these 12 isolates suggested that a specific clone of ETEC serotype O128:H45-CS21-ST2332 caused the nosocomial diarrheal among neonates. Of concern, this ETEC clone strain was resistant to multiple drugs, particularly the third-generation cephalosporins.

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