Article ID: JJID.2015.652
The urinary tract infection (UTI) is one of the most common infections in human, primarily caused by uropathogenic Escherichia coli (UPEC) that has a high multidrug resistance (MDR). Considering the prevalence of MDR-UPEC strains the aim of the present study was to systematically review published data about the prevalence rate of MDR-UPEC from different parts of Iran and provide an overall relative frequency (RF) for Iran. We searched several databases including PubMed, ISI Web of Science, Scopus, google scholar, IranMedex and Iranian Scientific Information Database by using the following keywords: “Escherichia coli”, “multi drug resistant”, “urinary tract infections”, “uropathogenic” and “Iran”. Articles/abstracts, which reported the prevalence of MDR-UPEC, were included in this review. We found 15 articles suitable for the inclusion in this study. Pooled estimation of 10247 UPEC strains showed that 49.4% [5% confidence interval (95%CI) =48-50.7%] of them were MDR positive. MDR-UPEC RF in different studies varied from 10.5% to 79.2% in Kashan and Hamedan provinces, respectively. According to the results of the present study, MDR-UPEC RF in Iran is in the high range. Thus, measures should be taken to keep the emergence and transmission of these strains to a minimum.
