Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
ISOLATION OF ADENOVIRUS FROM AN EXANTHEMATOUS INFECTION RESEMBLING ROSEOLA INFANTUM
HIDEO FUKUMIFUMIO NISHIKAWAYOSHIYUKI KOKUBUTOSHIKO NAKAYAMA
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JOURNAL FREE ACCESS

1957 Volume 10 Issue 2 Pages 87-91

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Abstract
It is now very clear that the adenovirus is a causative agent of pharyngo-conjunctival fever, but a couple of papers have reported a suggestion that the adenovirus might cause a kind of exanthematous infection. Neva and Enders (1954) isolated a cytopathogenic agent from an infant suffering from a roseola infantum-like disease, which was later classified as a member of adenovirus (Bell, Dingle, Francis, Hilleman, Huebner and Payne, 1956) . They isolated, however, this virus not from throat swab, infected tissues, or body fluid, but from faeces, and consequently presumed it not to be certain whether the virus isolated really caused the exanthem of the patient or it was there infecting the patient and as the result provoked antibody rise though her exanthem was produced by another virus that infected her simultaneously. On the other hand, Sohier (1956) in France described a patient showing “erythème morbilliforme” who was diagnosed as adenovirus infection by complement fixation reaction. Thus, a question is to be given rise about the relationship between the adenovirus and a kind of exanthematous disease.
Recently we encountered a patient of pharyngoconjunctival fever with measles-like exanthem from whom adenovirus was isolated as a causative agent. The present paper is dedicated to describe this patient and furthermore to discuss some considerations about the role of adenovirus in the exanthematous disease.
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