1958 Volume 11 Issue 6 Pages 461-465
In a previous paper (Fukumi et al., 1957), a cytopathogenic agent was reported to be isolated from an upper respiratory illness resembling an adenovirus infection. This virus was found to be different from each of the viruses such as polioviruses, Coxsackie viruses, adenoviruses, herpes simplex virus etc., but the cytopathic changes induced by it were like those due to the enteroviruses. The comparison of this virus with the ECHO viruses was not conducted at that time because neither the ECHO sera nor the ECHO viruses were not available to us. However thereafter when some of the ECHO viruses which were adapted to HeLa cells were given to us from Dr. M. Kitaoka, Department of Virology & Rickettsiology, National Institute of Health, Tokyo, experiments were carried out to determine whether or not the virus belonged to the group of the ECHO viruses. Further, serological examinations were made on various groups of people in order to know as to how widely the antibodies against the virus are distributed in them.