Abstract
Since 1960, a diarrheal disease, presumably related to Shigilla infection, has been observed among cynomolgus monkeys (Macaca irus) during quarantine at the Division of Animal Care, Branch Laboratory in Murayama, the National Institute of Health. Muto et al. (1963) and Takasaka et al. (1964) reported results of an epidemiological survey of the disease which placed emphasis upon the carrier status of Shigella bacilli. Honjo et al. (1964), furthermore, have succeeded in experimental infection of healthy monkeys with Shigella flexneri 2a isolated from the diarrheal animals.
The present work offers the histopathological observation made on the natural and experimental Shigella infections of monkeys, with additional survey on human materials of Shigellosis diagnosed clinically as Ekiri. The latter was made for the purpose of comparison of Shigellosis between monkeys and human beings.
