Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
A NOVEL TYPE OF LYMPHOCYTE-MACROPHAGE ASSOCIATION REVEALED ELECTRON MICROSCOPICALLY IN TUBERCULOUS LUNG LESIONS OF MICE
KOOMI KANAIEIKO KONDOTOMOYOSHI YASUDA
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1982 Volume 35 Issue 1 Pages 31-35

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Abstract
Electron microscopic survey of tuberculous lung lesions of mice revealed a novel type of lymphocyte-macrophage association. The finger-like projections with sharp or blunt tips of lymphocytes are formed as if pushing deeply the macrophage membrane to form pockets matching the shape of the projections. Intimate membrane contact occurs between these two cells, particularly at the leading edges. The biological significance of this morphological event remains to be a subject for future study.
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