Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
ISSN-L : 0021-5112
IMMUNOFLUORESCENCE FOR DETECTION OF VIRAL ANTIGEN IN MICE INFECTED WITH SENDAI VIRUS
EIKO SUZUKITAKESHI MUTOMASARO NAKAGAWAKIYOSHI IMAIZUMIKUNIAKI KINOSHITA
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1982 Volume 35 Issue 2 Pages 81-85

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Abstract
Sendai virus infection transmitted by contact from cagemates was followed by virus titration and immunofluorescence. The virus grew in the respiratory tract and caused macroscopic lesions in all contact mice. The virus grew to a higher titer in the lung than in the trachea. Tracheal smears, however, were found to be the most suitable for the diagnosis of Sendai virus infection by immunofluorescence, since they contained a large number of cells with intense fluorescence. Diagnosis of Sendai virus infection was made by immunofluorescence within a few hours after autopsy made at early stages of infection.
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