Japanese Journal of Medical Science and Biology
Online ISSN : 1884-2828
Print ISSN : 0021-5112
EFFECT OF ORALLY ADMINISTERED POLYSACCHARIDE FROM KEFIR GRAIN ON DELAYED-TYPE HYPERSENSITIVITY AND TUMOR GROWTH IN MICE
MITSUGU MUROFUSHIMICHIO SHIOMIKAGEAKI AIBARA
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1983 Volume 36 Issue 1 Pages 49-53

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Abstract

The effect of oral administration of a polysaccharide (KGF-C), isolated from the kefir grain, on delayed-type hypersensitivity (DTH) induced by picryl chloride and on the growth of solid tumor was examined in mice. KGF-C caused an increase in DTH response in intact mice and also tumor-bearing mice. The growth of tumor inoculated after the DTH test was markedly inhibited in the groups with high DTH response. A significant correlation between the DTH response and the antitumor activity was observed in intact mice.

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