Abstract
As one of the means for the serological diagnosis of neurotropic viral infections, the complement-fixation test proved to be of definite value and was widely applied at present. Complement-fixation test was performed on 226 Japanese encephalitis cases who had been admitted into the Ebara Hospital during the epidemic of 1948 in Tokyo. The results obtained from the sera withdrawn at their early period after onset, have been already reported, There are some reports described by other workers on the same problem. It seems, however, there is no report made on the tests performed covering a long period of time after convalescence.
For this reason, 14 out of above-mentioned 226 cases were bled continuously after discharge from the hospital. Their bleeding was continued for about two and half years till March 1951. Complement-fixation test was performed on each serum sample and collected neutralization test too was performed as much as possible. There are several papers on the neutralizing antibody examined for a long period after convalescence. An attempt was made to re-examine the neutralizing antibody curve in Japanese encephalitis cases to know whether the curve of neutralizing antibody has any relation to that of complement-fixing antibody.
Besides, complement-fixation test was performed on the sera obtained from the patient suffering from non-encephalitic diseases, who had been admitted to the Ebara Hospital and had no anamnesis of Japanese encephalitis, at several months intervals from 1948 to 1951. The results of complement-fixation test made on their sera were compared with those from convalescent cases.
