Abstract
Mexiletene hydrochloride (MexitilTM, hereinafter MX) is widely used in clinics as an anti-arrhythmic agent having a lidocaine-like structure. Here, we report on its use and effect for radicular pain (sciatica), with reference to the literature. The anti-arrhythmic agent mexiletene hydroghloride was administered to 22 neuralgia patients. Excluding the 3 cases with side-effects, satisfactory results were seen in 19 of 22 cases (86.4%). We concluded that this drug may exhibit an effect as a treatment agent for neuralgia patients.