X-ray microscopy experiments at synchrotron radiation facilities generally require X-ray imaging detectors with high spatial resolution and a wide field of view. For such purposes, lens-coupled X-ray imaging detectors are widely used. The SPring-8 X-ray microscopy beamlines require detectors that satisfy a 200 nm spatial resolution and over 50 mm field of view. We have demonstrated spatial resolution of 200 nm line-and-space patterns visualization by using photodiffusion-free transparent scintillator. For the field of view, we have carried out a systematic optical design based on an analytical optimization approach and elucidated that a set of five detector systems is able to meet these requirements while keeping near-diffraction-limited spatial resolution. Their objective lenses have magnifications of 20x, 7x, 5.2x, 3.5x, and 1x. All the systems are designed to be equipped with 150 Mpixel CMOS image sensors. To verify our optimization approach, we have built a detector system with a magnification of 3.5x. The detector has successfully resolved 1.2 μm line-and-space patterns for the entire field of view, which is close to the optical diffraction-limited resolving power of 1.0 μm line-and-space patterns.

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RRMD-III and PS-TEPC were developed as active space dosimeters. RRMD-III is a Si detector telescope and PS-TEPC is a gas time projection chamber. After their returning to the Earth, the energy calibration was performed again. Future prospects and the relationship between life in the coronal disaster and life in space will also be discussed.

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Perspectives on development of high temporal resolution PET detectors were discussed at a workshop held in Valencia, Spain in June 2022. In the workshop, researchers have discussed how we will develop the next generation PET systems towards 100 ps time-of-flight (TOF) PET. There are several challenges to make the 100 ps TOF-PET system practical although some research has achieved sub-100 ps coincidence time resolution at a laboratory level. The scope of the conference widely spans clinical motivation, system consideration, scintillator, photodetector, electronics, artificial intelligence, and image reconstruction. By putting them together, researchers believe that 100 ps TOF-PET system can be realized in near future. In this paper, the author will introduce several topics discussed in the workshop. In addition, the author share experience of the international workshop during the COVID-19 pandemic.

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