It is ultimately impossible for life on the Earth to survive in space without the science and technology of human beings. To enable human and life on the Earth of inhabiting sustainably in space environment, we need to create the new system of space science and technology by integrating existing sciences, such as physical science, life science, applied science, social science and art. The action principle of the Japan Society of Microgravity Application (JASMA) states: “We develop science and technology to solve the global problems that our society now confronts, using unique microgravity environment in space.” According to the principle, we carry on integrated research programs that consist of 1) basic research, 2) applied research, and 3) space project. In this paper, the roadmaps of microgravity-applied sciences are overviewed by reviewing the outputs of ISS experiments and a unified program of space environment utilization on the Moon is proposed as a post ISS program.
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