The initial phase of 6-month regemen of chemotherapy of pulmonary tuberculosis in children in this study consists of at least 2-month period of daily isoniazid, rifanpicin and pyrazinamide. The continuation phase is daily isoniazid and rifampicin for a further 4-months. Twenty-seven children with tuberculosis under 17 yr. of age were treated with this regemen from January 1992. Twenty-one of 27 cases had cured without relapse or side effects by this regemen. Six of 27 patients could not completed this regemen, because of side effects in two cases, abnormal liver function tests without jaundice caused by rifampicin and pyrazinamide respectively, drug resistance in two, cessation of treatment in one, and change to other clinics in one. 6-month regemen of chemotherapy of pulmonary tuberculosis in this study appeared to be effective and safe.

View full abstract

Although the relationship between aerobic types of exercise and exercise-induced bronchospasm (EIB) has already been well established, the influence of anaerobic exercise on EIB is still unknown.
The purpose of this study was to compaire the influence of aerobic exercise with that of intermittent anaerobic exercise on EIB in asthmatic children.
Seven children with bronchial asthma participated in this study. The subjects underwent an incremental anaerobic exercise test to determine their maximal anaerobic power (Pmax) with a high power cycle ergometer. Each subject then underwent an anaerobic EIB tests which was 10 repetitions of 10 seconds anaerobic exercise with intervals of two minutes. Exercise intensity was 60%, 80% and 90% of Pmax respectively. They also performed an aerobic EIB test for 6 min by standard method.
The results were follows.
1. The average maximal anaerobic power (Pmax) was 473.2±131.1 watt. The avarage rpm. and torque at Pmax were 100.8±5.8 rpm and 4.6±1.3 kp respectively.
2. There was no significant difference in total work between aerobic exercise and 80% Pmax and 90% Pmax of anaerobic test.
3. Minute ventilation was significantly lower during intermittent anaerobic exercise tests compaird with aerobic exercise test.
4. Max % fall in FEV_1.0 in aerobic exercise test was 21.8±13.1%. All of subjects did not show a fall in FEV_1.0 more than 10% after intermittent anaerobic exercise tests.
Based on these results, it was concluded that intermittent anaerobic exercise was safer than aerobic exercise.
Therefore, intermittent anaerobic exercise training may be recommended to asthmatic children.

View full abstract

We reported a case of a previously healthy 14 years old boy, had chest pain due to spontaneous pneumothorax of the right lung. Continuous drainage was not successful so that thoracotomy was performed and bullae were resected. Histologically, aspergilloma was found in the cavity. It is reported that pulmonary aspergilloma associated with chemotherapy induced immunodeficiency during childhood has been increasing. However pulmonary aspergilloma without previous immunodeficiency is considered to be quite rare. We conclude that even during childhood previously healthy children may have pulmonary aspergilloma. Serological allergic reaction and histological examination are important to decide therapeutic plan in spontaneous pneumothorax.

View full abstract