Sampling of biopsies from almost every human organ is possible, except the brain. To study the molecular changes brain, use of post mortem samples are the only option. The main issues of brain banking in Taiwan are the difficulty in obtaining sustainable funding and humanly issues. A collaborative primitive setting that stores the previously collected and newly collected brain samples, is the first step to start. The second issue is to maintain the sense of glory and nobleness for the donators and their relatives, as this is more important than the knowledge that the brain creates.