When employing multimodal images, adjusting scales and positions between them by determining spatial correspondences is necessary, and in surgical navigation combining real space where a patient is present and virtual space in a computer is necessary. These are an operation determining corresponding relations between images etc. represented at different coordinates, and called “registration”. Registration is the most important fundamental technique in surgical navigation and in dealing with different images, and a lot of efforts have been made in developing this technique. Though the registration technique was developed originally in industrial field, it has become remarkably advanced recently in medical imaging field, and presently it has power to pull the industrial field. Recently, two specialized books on registration were published successively. In the present article, registration techniques are explained from technical view point including the latest research trend.
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