By the application of quantification model No.2 an attempt was performed to make a diagnosis of functional disorders of the liver in dairy cows on the basis of general symptoms and the results of simple laboratory examination.
Trial 1 was carried out on 51 Holstein cows. As a result, it was possible to obtain a discriminant function for the diagnosis of functional disorders of the liver in cows on the basis of appetite, energy, consistency and form of feces, pulse, occult blood, reaction, hemoglobinuria and hematuria, and results of examination on the pH of urine.
Trial 2 was conducted to determine whether the discriminant function obtained in the preceding trial was available for the diagnosis of hepatic dysfunction in the everydail practice of buiatrics or not. As a result, a positive diagnosis of hepatic dysfunction was made successfully by the application of this function in nine of eleven cows in which the bromsulphalein test had revealed the same hepatic dysfunction. On the other hand, when a diagnosis of slight depression of the function of the liver was made in six cows by the bromsulphalein test, an erroneous diagnosis of abnormality in the function of the liver was made in five of these cows by the application of the discriminant function obtained in trial 1 and used for diagnosis. It was not made, however, in any dairy cow with a normal hepatic function.
It was concluded from these studies that the discriminant function obtained in trial 1 was applicable to a screening test of cattle affected with abnormality in the function of the liver in the field, on condition that cattle with slight depression of the function of the liver were regarded as those with mild abnormality in the function of this organ.
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