It is known that the pattern present on the animal’s skin is a kind of wave (Turing pattern) created by the interaction between pigment cells. Basically, the patterns of all species are made on the same principle, the difference of patterns by species depends on subtle differences in interaction. So, if you find a molecule responsible for its interaction and artificially change its function, it should be possible to change the pattern. Our research group has revealed the interaction between pigment cells through molecular genetic experiments using zebrafish over the last two decades. Molecules responsible for interaction are already evident. By manipulating these genes, we are able to freely convert zebrafish patterns. Because the principle of pattern formation is probably the same for mammals, now, it is not impossible to change the skin of giraffe to the pattern of zebra horse.

Cosmetics and medicated cosmetics are recognized as a necessity of daily life to increase the quality of life, and are used to maintain health and increase beauty. Cosmetics and medicated cosmetics are mainly regulated by The Law on Securing Quality, Efficacy and Safety of Products Including Pharmaceuticals and Medical devices. The main purpose of the Law is to improve public health, and to achieve this, securement of the quality, efficacy, and safety of cosmetics etc. is required. To fulfill the purpose, it is necessary to understand the regulation for cosmetics and medicated cosmetics accurately and to follow the Law properly. In this report, the definition of cosmetics and medicated cosmetics, regulations on ingredients and efficacy-effects, and regulations for selling cosmetics etc. are described.