Phosphorus Research Bulletin Vol. 33(2017)

Editorial Board

Released: April 27, 2017

p.i-

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MICROCRACKS DESIGN AND BONE INDUCTION OF SKULL BONE MODIFIED BY ULTRASONIC TREATMENT USING ACIDIC ELECTROLYZED WATER

MAMATA SHAKYA, MASARU MURATA, NAOTO OKUBO, HIROKI NAGAYASU, TOSHIYUKI AKAZAWA

Released: April 27, 2017

p.1-6

Healthy bone has many physiological microcracks, which may be involved in the release of bone matrix-derived factors and act to accelerate bone-remodeling process. In this study, the mouse parietal bone fragments (5x5x1mm³) were demineralized by acidic electrolyzed water (AEW: pH2.7) or distilled water (DW: pH5.2) at 120W and 38KHz for 20 min. Each bone was implanted into subcutaneous tissue of 10 week-old male nude mouse, and explanted at 4 and 6 weeks. AEW-bone showed clear enlargement and union of cracks on SEM. AEW-bone revealed active bone induction over wide areas at 6 weeks, while DW-bone induced new bone in limited area. We concluded that the AEW-bone had better performance in bone induction than the DW-bone. Our micro-damage technique combined with AEW and the ultrasonic irradiation will contribute to improve surface area and 3D structure of the dense bone and promote bone formation in the initial stage for bone remodeling.

EFFECTS OF ADDITION OF α-TRICALCIUM PHOSPHATE POWDERS ON MATERIAL PROPERTIES OF THE CHELATE-SETTING HYDROXYAPATITE CEMENT

Keishi Kiminami, Kento Matsuoka, Toshiisa Konishi, Minori Mizumoto, Michiyo Honda, Hidetoshi Arimura, Mamoru Aizawa

Released: April 27, 2017

p.7-13

We have previously developed a chelate-setting calcium-phosphate cement (CPC) consisting of hydroxyapatite (HAp) powders surface-modified with inositol hexaphosphate (IP6). In the present study, mechanically ball-milled α-tricalcium phosphate (α-TCP) powders were added into the IP6-HAp cement in order to enhance its anti-washout capability and mechanical properties. After optimization of the ball-milling conditions, the cement specimens mixed with various amounts of the prepared α-TCP powders were fabricated. Examinations of their mechanical properties revealed significant increase of compressive strength (CS) with the addition of the α-TCP powders. Further, it was demonstrated that the specimens of the IP6-HAp powders / the α-TCP powders mixing ratios of 20/80 and 30/70 [g/g] exhibited comparatively high anti-washout capability. In conclusion, these cements are promising chelate-setting CPCs with enhanced anti-washout capability and mechanical properties.

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Phosphorus Research Bulletin

Phosphorus Research Bulletin Vol. 33(2017)

Editorial Board

MICROCRACKS DESIGN AND BONE INDUCTION OF SKULL BONE MODIFIED BY ULTRASONIC TREATMENT USING ACIDIC ELECTROLYZED WATER

EFFECTS OF ADDITION OF α-TRICALCIUM PHOSPHATE POWDERS ON MATERIAL PROPERTIES OF THE CHELATE-SETTING HYDROXYAPATITE CEMENT

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Volume And Issue List Phosphorus Research Bulletin

Phosphorus Research Bulletin Vol. 33(2017)

Editorial Board

MICROCRACKS DESIGN AND BONE INDUCTION OF SKULL BONE MODIFIED BY ULTRASONIC TREATMENT USING ACIDIC ELECTROLYZED WATER

EFFECTS OF ADDITION OF α-TRICALCIUM PHOSPHATE POWDERS ON MATERIAL PROPERTIES OF THE CHELATE-SETTING HYDROXYAPATITE CEMENT

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Phosphorus Research Bulletin