Sequential Oxidation and Reduction of Some Methyl 4, 6-O-Benzylidene-α- and β-D-Glucopyranoside Derivatives

Abstract

Reduction of methyl 4, 6-O-benzylidene-α- and β-D-glycopyranosidulose derivatives with sodium borohydride was carried out. From the yield of the axial and equatorial epimers, a possible mechanism of the borohydride reduction and factors determining the directions of the reagent's attack to a carbonyl group are discussed.